Skin care is deeply personal. From scent and texture to ingredients and pricing, building a routine is all about preference. But when it comes to mature skin, one thing matters most: results.
When we asked more than 400 NewBeauty readers* to name their favorite skin-care product, one serum rose to the top for its ability to visibly transform skin: SkinMedica TNS Advanced+ Serum. Powered by growth factors, this high-performance formula earned praise across every age group, but mainly those over 50, for delivering fast, noticeable results.
At 58, one reader said it “improves fine lines, tone and texture.” Another, 71, shared: “I can see a real difference in my skin in overall firmness and tone. No one believes my age when I tell them.” At 53, one fan said it “makes my face feel taut and smooth,” while a 47-year-old called out its impact on “tightening, elasticity, [and] skin tone.”
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Even younger users are turning to it for prevention. A 31-year-old said it “helps prevent wrinkles,” while a 26-year-old simply called it “anti-aging.” At 45, one reader said it “helps slow aging,” and at 52, another shared: “It helps me feel younger.”
Though it’s a splurge, readers say it’s worth it. “Yes, it’s expensive,” said a 44-year-old, “but you see results pretty quickly. Smoother, more lifted, more radiant.” And at 57, one user summed it up: “I can feel my skin tighten when it’s applied and it keeps my skin firm and wrinkle-free.”
From early prevention to visible transformation, this serum continues to be a top pick for readers who want real results fast.
*Source: BeautyEngine Advanced Research, 2025
