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From SPF to Serums, These Brands are Breaking the Skin-Care Mold

Forget what you thought you knew about skin care.

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nb100 skin care brands

Whether they’re simplifying routines, making SPF cool or turning acne care into a moment of joy, each one of these award-winning skin-care brands brings something new—and necessary—to the modern beauty conversation.

From SPF to Serums, These Brands are Breaking the Skin-Care Mold

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Anua

Anua keeps things calm and simple with gentle, K-beauty formulas—like its cult-favorite Heartleaf line—that actually work.

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Anua
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banu

Banu takes a clean, barrier-first approach to acne care with non-comedogenic formulas that support real, lasting results.

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banu
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Barefaced

Barefaced simplifies skin care with medical-grade essentials that deliver results without the overwhelm.

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Barefaced
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Elm Biosciences

Cofounded by Martha Stewart, Elm Biosciences blends advanced antioxidant science with luxury skin care that works from the inside out.

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Elm Biosciences
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Epicutis

Epicutis delivers clean, clinical skin care with science-backed ingredients that calm inflammation and support long-term skin health.

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Epicutis
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ERLY

ERLY makes skin care easy for tweens and beyond with gentle, effective formulas that build healthy habits from the start.

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ERLY
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Hydrinity

Hydrinity brings injectable-grade hyaluronic acid to your daily routine with luxury formulas trusted by pros and skin-care obsessives alike.

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Hydrinity
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Lenox and Sixteenth

Designed to streamline your routine without cutting corners, Lenox and Sixteenth delivers luxe, clinical-grade formulas that multitask like a pro.

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Lenox and Sixteenth
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LINES by Dr. Marnie

Designed to complement in-office treatments, LINES brings New York’s favorite derm home with clean, clinically proven essentials.

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LINES by Dr. Marnie
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Parëva Beauty

Parëva Beauty blends plant biotechnology with radical transparency to deliver skin care that visibly transforms—no guesswork required.

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Parëva Beauty
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Personal Day

Founded by Lili Reinhart, Personal Day makes clean, compassionate skin care for acne-prone skin that’s affordable and actually enjoyable.

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Personal Day
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Qure Skincare

Qure turns clinical skin tech into personalized, at-home solutions that adapt to your skin’s unique needs.

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Qure Skincare
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SickScience

SickScience brings regenerative skin care into the mainstream with patented, plant-derived exosomes that deliver real, visible results.

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SickScience
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Sofie Pavitt Face

Created by NYC’s go-to acne expert, Sofie Pavitt Face is a no-fluff, three-step system that clears skin without the drama.

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Sofie Pavitt Face
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Wildfleur

Wildfleur treats flowers like science, delivering biocompatible, clinically proven actives that make high-performance skin care more accessible than ever.

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Wildfleur
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Bubble Skincare

With dermatologist-developed formulas and plant-based ingredients, Bubble makes skin care feel fresh, fun and totally accessible for a new generation.

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Bubble Skincare
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BYOMA Skincare

BYOMA simplifies skin care with barrier-boosting formulas that are easy to understand, affordable and seriously effective.

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BYOMA Skincare
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DEINDE

Focused on inflammaging and barrier repair, DEINDE delivers streamlined skin care that works hard so you don’t have to.

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DEINDE
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DUNE Suncare

DUNE makes SPF feel cool again with nearly invisible formulas that are effortless to apply and easy to love.

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DUNE Suncare
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Filterbaby

Clinically proven to remove up to 99 percent of skin-irritating toxins, Filterbaby turns your tap water into a skin-care step.

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Filterbaby
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INNBEAUTY Project

INNBEAUTY Project delivers clean, high-performance skin care that’s bold, effective and refreshingly affordable.

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INNBEAUTY Project
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Lion Pose

Created by a Harvard derm and backed by Mindy Kaling, Lion Pose tackles tough skin concerns with clinically tested, prescription-adjacent formulas.

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Lion Pose
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Mother Science

Mother Science blends cutting-edge research with natural ingredients like malassezin to deliver visible results without the harsh side effects.

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Mother Science
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Naked Sundays

With SPF-packed formulas that double as skin care and makeup, Naked Sundays makes sun protection feel like a treat, not a chore.

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Naked Sundays
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Naturium

Naturium bridges science and nature with clinically backed, botanically powered formulas that deliver real results at real-world prices.

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Naturium
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Oak Essentials

From the mind of Jenni Kayne, Oak Essentials is clean, luxurious skin care that feels as effortless and elevated as her signature aesthetic.

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Oak Essentials
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Prakti

Prakti pairs ultra-luxe textures with comforting, results-driven formulas that feel as nurturing as they are effective.

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Prakti
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Prequel

Prequel offers derm-developed skin care that’s simple, affordable and designed to support your skin’s story.

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Prequel
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Provence Beauty

Provence Beauty brings a modern twist to French beauty with clean, effective formulas all under $25.

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Provence Beauty
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rhode

Founded by Hailey Bieber, rhode delivers skin-nourishing essentials that make achieving a dewy, healthy glow feel effortless and accessible.

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rhode
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Saie

Saie merges clean, conscious beauty with high-performance formulas and sustainable packaging that look as good as they feel.

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Saie
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Saltyface

Saltyface makes sunless tanning foolproof with clean, streak-free formulas that deliver a believable glow.

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Saltyface
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Starface

With its iconic pimple patches and playful packaging, Starface brings joy and confidence to acne care for all ages.

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Starface
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toty

Backed by Sofia Vergara and built on best-in-class SPF, toty makes sun protection feel luxurious, effective and totally non-negotiable.

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toty
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U Beauty

U Beauty streamlines skin care with multi-tasking, science-backed formulas that deliver visible results with fewer steps.

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U Beauty
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Vacation

Vacation rebranded SPF as the coolest step in your routine, with nostalgic scents, chic packaging and serious sun protection.

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Vacation
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Versed

Versed delivers derm-tested, community-developed skin care that’s effective, sustainable and always under $25.

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Versed
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YSE Beauty

Founded by Molly Sims, YSE Beauty pairs glow-boosting formulas with a mission rooted in kindness, sustainability and marine conservation.

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YSE Beauty

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