The Best Moisturizers for Skin Over 50, According to Experts

The Best Moisturizers for Skin Over 50, According to Experts featured image
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Getting older can sometimes feel like a punishment: seeing wrinkles and crepey skin staring back at us in the mirror when we feel as young and energetic as ever on the inside. Aging is a luxury—it means more time doing the things we love with the people we love—but it’s OK not to love what it does to your skin. To keep skin hydrated, healthy and youthful-looking, a good moisturizer is paramount.

Boston facial plastic surgeon Jaimie DeRosa, MD says that as we age, our skin “starts to show the wear and tear, so to speak, from environmental damage. Specifically, skin begins to lose hyaluronic acid, collagen and elastin, and the production of oil also decreases, all of which result in thinner, drier skin and the development of wrinkles. External ‘environmental’ factors, including UVA sun rays, can also lead to solar elastosis—think thickened, bumpy and tough skin—and pigmentation changes or age spots.” Here, top skin-care experts share their picks for best moisturizer for aging skin.

What to Look For in a Moisturizer for Mature Skin

“The ideal moisturizer for people over 50 must consider how to hold on to moisture with emollients like ceramides and squalene. But, it also must consider how to replenish it with humectants, such as glycerin and hyaluronic acid,” says Davie, FL dermatologist Marianna Blyumin-Karasik, MD. “As we age, these natural repairing and hydrating elements are diminished in our skin and no longer restored at the same rate. Therefore, we need the assistance of various moisturizing and fortifying ingredients to strengthen skin resilience and radiance. Additionally, many individuals age 50 and older are looking for multitasking products that can also help to improve the signs of aging by restoring elastin and collagen. Some of these include peptides, niacinamide and various antioxidants.”

Though in-office treatments remain the most effective way to visibly turn back the clock, moisturizers are essential in a daily skin-care regimen. “In your 50s, it’s important to focus on improving the dermal layer, providing proper moisture to the epidermis. Continuing to encourage collagen and elastin renewal and turnover is critical, too,” explains Mila Davis, aesthetician at Skin to Smile. “Although there are an endless number of moisturizers available on the market, there are important ingredients they should contain to help satisfy their effectiveness.” 

Top Moisturizers for Skin Over 50, According to Experts

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SkinCeuticals Triple Lipid Restore 2:4:2 ($155)

“Moisturizers is a category that I generally advise patients to not splurge on, however if you are going to splurge, this is the product you want to be purchasing. Its patented lipid ratio of 2-percent ceramides, 4-percent cholesterol and 2-percent fatty acids intensely nourishes skin and repairs the moisture barrier.” —Riverside, RI dermatologist Tiffany Libby, MD

“Triple Lipid Restore provides 24-hour hydration, which is key for mature, 50-plus skin. Skin hydration levels greatly diminish as we age. It also contains lipids, fatty acids, cholesterols and ceramides to give dry, dehydrated or mature skin a plump, radiant glow. It helps texture and pores look more refined as well.” —Fresno, CA dermatologist Kathleen Behr, MD

“Triple Lipid Restore restores essential skin lipids, including ceramides, natural cholesterol and fatty acids, that naturally diminish in the skin as we age. This lipid loss contributes to visible signs of aging and compromises our skin’s natural protective barrier, so Triple Lipid is very restorative for older patients experiencing these changes.” —New York dermatologist Julie Russak, MD

“This moisturizer is great for maintaining the skin barrier and promoting collagen and hydration, and I like that it is rich but not heavy.” —Melville, NY dermatologist Kally Papantoniou, MD

“This moisturizer from SkinCeuticals is great for people over 50, as it replenishes the ceramide barrier!” —Delray Beach, FL dermatologist Dr. Janet Allenby



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Medik8 Total Moisture Daily Facial Cream ($49)

“As we age, our skin’s cellular renewal processes slow down and so the impacts of environmental stressors and naturally occurring factors take more of a toll on our skin. This is why it’s important to use products that help to protect the skin’s barrier and support a healthy microbiome. This moisturizer  has a unique combination of prebiotic peptide strains and multiweight hyaluronic acid, as well as ceramides, which work together to support all aspects of your skin’s health.” —New York dermatologist Dendy Engelman, MD



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ELEMENT EIGHT O2 Growth Factor Eight Active Cream ($275)

“This cream was designed to help mature skin from both a technology and delivery approach. It is unique because it is formulated with a double dose of groundbreaking biomimicry technologies, which include OATH: Oxygen Amplified Therapy, the topical hemoglobin that delivers liquid oxygen directly to skin cells. It also includes a Penta Growth Factor Complex that optimizes the key physiological processes of the skin cell cycle, enhancing cell turnover, as well as improving collagen and elastin synthesis. 

This nourishing, multitasking moisturizer reduces the appearance of fine lines and wrinkles, builds collagen, enhances firmness and elasticity, intensely hydrates, improves skin barrier protection, provides antioxidant protection, calms, and soothes irritated skin. The texture itself is rich, luxurious, nourishing and deeply hydrating. It’s formulated with ceramides, squalane and multiple molecular weight hyaluronic acid to penetrate all levels of the skin, leaving all skin types with a nourished, healthy and radiant glow.” —Beverly Hills, CA dermatologist Nima Gharavi, MD



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Hydrinity HYDRI-C Daily Vitamin C Moisturizer ($150)

“As we age, fine lines become more prominent and sunspots are more evident. Moreover, our skin becomes more dry and dull due to decreased structure from collagen and elastin loss. One of the best at home tools to combat and correct mature skin is this moisturizer. It is as powerful as pharmaceutical products, but less irritating to the skin, as it utilizes a patented MicroFusion Technology to effectively deliver active ingredients deep into the dermal layer. This leads to enhanced collagen production, wrinkle reduction, improved skin elasticity, and evening of skin tone. This is not your mother’s vitamin C. It is the next generation.” —Houston dermatologist Suneel Chilukuri, MD

BUY NOW – $150

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PCA SKIN HydraBright ($100)

“HydraBright is particularly beneficial for individuals aged 50 and older, as it contains niacinamide, gallic acid and squalane. These ingredients help improve skin hydration and diminish the appearance of dark spots and hyperpigmentation. The formula aims to hydrate and brighten the skin, enhancing a youthful and radiant appearance. The cloud-like texture also provides a supreme experience for anyone when doing their skin-care routine.” —Celebrity aesthetician Ian Michael Crumm



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Elizabeth Arden’s Eight Hour HydraPlay Skin Perfecting Daily Moisturizer ($45)

“This is an effective moisturizer that instantly boosts the skin’s hydration by 64 percent, as well as provides eight other benefits for the skin. The claims speak for themselves: The consumer study revealed after just two weeks, 97 percent saw their skin become smoother and brighter, 94 percent saw improvement in their skin’s clarity, and 100 percent found their skin tone looked more even. 

For those with mature skin, the hyaluronic acid and glycerin ingredients included help hydrate and plump the look of skin, as well as strengthen the skin’s moisture barrier. As the skin develops in age, these are key ingredients when looking for a moisturizer that will support the look and feel of younger looking skin. The formula is also gentle enough for all skin types—including sensitive skin—dermatologist-tested and non-comedogenic.” —New York dermatologist Dendy Engelman, MD



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Alastin Skincare Restorative Skin Complex ($230)

“This moisturizer contains antioxidants like niacinamide and vitamin C, as well as polypeptides and moisturizing ingredients formulated in TriHex technology to help support new collagen and elastin formation.” —New York dermatologist Elaine Kung, MD

BUY NOW – $230

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Caudalie Premier Cru The Rich Cream ($129)

“It contains glycerin, lipids, shea butter, grape seed and olive oil and their proprietary hyaluronic acid, which makes it highly moisturizing. This is important as skin ages and is less able to retain moisture. It also contains Caudalie’s patented resveratrol, a potent antioxidant that may promote sirtuins, which are epigenetic protein regulators of aging. It’s also vegan and contains 97-percent natural-origin ingredients, which some people consider when choosing products.” —Nanuet, NY dermatologist Heidi Waldorf, MD



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Mary Kay Hydrating Moisturizer ($20)

“I recommend this moisturizer as a twice-daily topical application, as it gently nourishes all skin types and is excellent for mature skin. It combines a nourishing blend of elegant ingredients, including vitamin E, a well-established antioxidant, and natural botanical extracts such as sunflower oil, which delivers daily necessary hydration day and night.” —New York dermatologist Jared Jagdeo, MD

BUY NOW – $20

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Cosmette Timeless Hydration ($59)

“As skin ages and its structures change, how we maintain softness and retain moisture and hydration change too. One of the biggest challenges can be maintaining moisture and hydration while not weighing the skin down under layers of heavy ingredients. This moisturizer combines meadowfoam seed oil and rose hip seed oil to nourish the skin and provide moisture and tamanu seed oil to encourage collagen production, as well as multiple weights of hyaluronic acid to retain natural water balance. It provides long-lasting softness while remaining light and weightless on your skin. This means it can be used by anyone with skin types ranging from oily to dehydrated/dry skin without worrying about greasiness, heaviness or breakouts.” —Laura Richey, aesthetician at Laura Richey Esthetics in Nova Scotia

BUY NOW – $59

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BIOEFFECT EGF Power Cream ($219)

“This luxe, dense cream is a nutrient-rich hydrator powered by a barley beta glucan, which is an important anti-inflammatory. It reduces oxidative stress and the appearance of lines and wrinkles, but also has this incredibly rich blend of emollients and ceramides that are deeply nourishing while supporting the skin barrier and stopping losses of firmness and skin density.” —Beverly Hills, CA dermatologist Ava Shamban, MD



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Kiehl’s Ultra Facial Cream ($67)

“This best-selling cream has squalane in it, which is part of our skin’s natural sebum and becomes less productive as we get older, resulting in drier skin. It’s fantastic for people with more mature skin.” —New York dermatologist Michelle Henry, MD



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CeraVe Moisturizing Cream ($17)

“This is a nice budget-friendly hydrating moisturizer with ingredients including hyaluronic acid and ceramides that help to hydrate the skin and protect it from external damage by strengthening its barrier function. These ingredients help make older, drier skin look better by hydrating and plumping it up.” —Dr. DeRosa

“CeraVe Moisturizing Cream contains three important ingredients: hyaluronic acid, ceramides and glycerin. Ceramides and glycerin are effective in protecting the skin barrier and locking in moisture, while hyaluronic acid will promote smoother skin texture and improve the visibility of fine lines and wrinkles.” —Mila Davis



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PURA D’OR Radiance AM Face Cream ($30)

“This is a great daytime moisturizer option for mature skin, as it combines antioxidants like green tea, edelweiss and methylene blue. These not only help protect against daily environmental stressors, but also reduce inflammation and can even upregulate elastin and collagen production, all issues that increase as we age. Additionally, using an antioxidant-rich product during the day helps to support the skin’s own circadian rhythm, enhancing the skin’s defense mechanisms.“ —Aesthetician Katie Sobelman



pura dor radiance moisturizer
15 / 31

AlumierMD Ultimate Boost Serum ($105) 

“This is a lightweight serum that boosts hydration and enhances the skin’s natural hydrolipid barrier with sodium hyaluronate and niacinamide. MATRIXYL Synthe’6 strengthens the skin and reduces the appearance of fine lines and wrinkles. Perfect to use as a booster under moisturizer, both morning and night. I love this product for patients 50 and older because mature skin is thinner and drier, and this is a true multitasker. It’s very hydrating, and the mixture of antioxidants also provides rejuvenating benefits.” —New York dermatologist Marina Peredo, MD

BUY NOW – $105

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skinbetter science Trio Rebalancing Moisture Treatment ($155)

“This moisturizer contains hyaluronic acid and is designed to rehydrate mature skin. It is also very good if you have sensitive skin.” —Rochester, NY dermatologist Lesley C. Loss, MD

“This is absolutely amazing for those who want all the hydration without any of the shine. It contains omega-6 and omega-3 essential fatty acids that support the skin’s barrier and deeply hydrates, diminishing the look of fine lines and wrinkles. It’s perfect in the summer when you do not want your moisturizer to feel thick and heavy.” —Celebrity aesthetician Morgan Rackley

BUY NOW – $155

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Biossance Squalane Omega Repair Cream ($60)

“This is a rich, decadent cream full of lipids like omega fatty acids, squalane and ceramides. It feeds the face with a plumping effect!” —Dr. Shamban



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Olay Regenerist Retinol24 + Peptide Night Face Moisturizer ($30)

“This fragrance-free nighttime moisturizer contains both retinol and retinyl propionate for a more potent treatment. It firms, smooths, brightens and hydrates your skin.” —Dr. Adrienne O’Connell, medical director and president of Laguna Beach Aesthetics



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Alastin Ultra Nourishing Moisturizer ($88)

“This moisturizer contains essential fatty acids and lipids to maintain the skin barrier and improve hydration, aat kernel extract to soothe, and the brand’s proprietary peptide complex to renew collagen and elastin.” —Dr. Waldorf

BUY NOW – $88

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iS Clinical Reparative Moisture Emulsion ($105)

“This formula contains moisturizing ingredients, antioxidants, polypeptides, retinol, and superoxide dismutase, which helps protect skin from pollution and ultraviolet damage.” —Dr. Kung

For skin over 50, we are usually trying to increase hydration and firmness, diminish fine lines and wrinkles, and induce collagen production. This is one of my absolute favorite moisturizers for this because it contains growth factors to help with firmness, improves deep and surface hydration and helps prevent further environmental damage. I also like that it’s great for all skin types, including those that are oily or have acne.” —Morgan Rackley



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ARCONA Magic Dry Ice ($65)

“Applying extra layers of richer moisturizer won’t always remedy dry, flaky skin. Generally speaking, you want a moisturizer like this one that has ingredients that can support the skin’s lipid barrier and prevent moisture loss. Some of my favorite ingredients in a moisturizer for winter skin contain any of the following: glycerin, squalane, safflower, borage, cholesterol, ceramides, sweet almond, and shea butter.” —Chanel Jenae, aesthetician, owner and creative director of ARCONA



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Alphascience Ultra Deep ($128)

“Older, mature skin often requires more TLC than that of younger skin, so the best moisturizers for those age 50 and older are those that actually work to reverse signs of aging and also help improve hydration and skin tone. These ‘age reversing’ ingredients are those that help to stimulate the creation of new collagen, elastin and hyaluronic acid, while also reducing fine lines, wrinkles and hyperpigmentation/age spots.

This anti-aging cream is a heavy-hitter in that it targets skin that already shows moderate-to-severe aging changes.  Paraben-free, with botanically derived ingredients, it is great for those with normal-to-dry skin and can be used morning and night on the face, neck and décolleté. It also includes genistein, an isoflavone and rich antioxidant that helps to increase the production of collagen and decrease collagen breakdown by blocking metalloproteases MP1 and MP3.”  —Dr. DeRosa

BUY NOW – $128


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Reserveage Beauty Firming Face Cream ($30)

“Besides being an incredible moisturizer with ceramides and lactic acid to gently exfoliate, this anti-aging cream also has copper-encapsulated peptides that help improve appearance of fine lines and wrinkles and support collagen and elastin production for firmer and softer skin.” —Dr. Libby



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NeoCutis Bio Cream Firm Riche ($208)

“This is my favorite moisturizer because of its beautiful texture, fragrance-free formulation and high percentage of growth factors. I recommend it to my patients who need a little more hydration and anti-aging at the same time.” —San Francisco dermatologist Tracy Evans, MD



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DOCTOR BABOR LIFTING RX Collagen Cream ($124) 

“This is my personal favorite! As we age our skin becomes more dehydrated, leading to lackluster skin and more visibility of fine lines and wrinkles. We also lose collagen and elastin, and frankly, we make less as well, therefore important ingredients include hyaluronic acid and squalene to boost skin’s moisture content, and marine collagen and tripeptides to fortify the skin’s surface by improving skin elasticity and firmness.” —Miami dermatologist Roberta Del Campo, MD


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Revision Skincare D.E.J Night Face Cream ($178)

“This is a great moisturizer that contains a micro-encapsulated time-released 0.25-percent retinol and also its ‘cousin’ bakuchiol, which works in a manner similar to retinol without irritation and the typical side effects of retinol, making this cream well-tolerated. Retinol is great at combating aging skin, as it works at the cellular level to help reduce inflammation, increase cellular regeneration and decrease wrinkle formation. It even works to reduce hyperpigmentation and shrink the appearance of pores, too. Moreover, this moisturizer contains 11 antioxidants to help prevent further environmental damage while reducing photodamage and fine lines and wrinkles, and improving skin’s elasticity and moisture.” —Dr. DeRosa




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Emepelle Night Cream ($195)

“This is the only clinically proven moisturizer composed of innovative anti-aging properties that reverse the signs of estrogen deficiency. This leaves skin more vibrant and hydrated with improved elasticity and the reduced appearance of fine lines and wrinkles.” —New York dermatologist Amy Lewis, MD



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Avène RetrinAL 0.1 Intensive Cream ($79)

“This retinaldehyde-containing cream helps smooth appearance of fine lines and deep furrows and brightens skin, making it a great option for mature skin.” —Dr. Libby



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La Roche-Posay Toleriane Double Repair Face Moisturizer ($24)

“This moisturizer contains several important ingredients including ceramides, glycerin, niacinamide, and the added benefit of SPF. Niacinamide helps maintain the lipid barrier and maintain moisture, more importantly it is compatible with all skin types.” —Mila Davis



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LilyAna Naturals Retinol Cream ($30)

“This cream is unique in that it contains hyaluronic acid, vitamin E, green tea, shea butter, and jojoba oil to provide proper moisture and hydration while packing an anti-aging punch with one of the most potent ingredients used in fighting lines and wrinkles, retinol.” —Mila Davis

BUY NOW – $30

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DOCTOR BABOR LIFTING RX Instant Lift Effect Cream ($135)

“This is a truly unique product with powerful active ingredients to not only provide immediate correction, but also slow down the aging process. It features oligosaccharides for an instantly smoothing effect on lines and wrinkles, swertia chirata extract to support the rejuvenation of skin cells and strengthen the skin barrier, and edelweiss stem cells. The defenses that so efficiently protect the edelweiss plant in harsh climates are used to protect human skin and reverse the signs of aging.” —Dr. Del Campo



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