This New Exosome Innovation Transforms Your Skin After In-Office Treatments

Everyone is talking about exosomes these days, but not all exosomes are created equal. In fact, they come from a variety of different sources and some are more efficacious than others. In recent (and exciting) news, the scientists at Dermalogica have unlocked a new frontier in exosomes. “Exo Booster represents a global breakthrough as the first bacterial exosome system in regenerative skin care,” says Manhattan Beach, CA dermatologist Glynis Ablon, MD. Read on to learn about this breakthrough innovation and its ability to transform skin.

• Glynis Ablon, MD, a dermatologist based in Manhattan Beach, CA
• Ted Vuong, a nurse practitioner and founder of Skin 22 Concierge Skin in Beverly Hills, CA

“Exosomes are small extracellular vesicles that are naturally secreted by cells to act as cellular messengers,” says Dr. Ablon. “They contain bioactive molecules like proteins, lipids and nucleic acids that influence the behavior of recipient cells.” Essentially, exosomes can be used topically to help our skin act and look younger. “They are trending because of their innovative, revolutionary role in increasing cellular recovery,” adds Ted Vuong, nurse practitioner and founder of Skin 22 Concierge Skin in Beverly Hills, CA. “Exosomes facilitate cell-to-cell communication, delivering powerful growth factors and signals to stimulate repair and renewal. Unlike traditional skin-care ingredients, exosomes work at the cellular level, making them a game-changer in advanced aesthetics.”

Instead of sourcing exosomes from humans or plants, they are derived from Lactobacillus bacteria using plant-based fermentation. “Backed by clinical studies across the United States, UK, and Italy, these vegan exosomes consistently demonstrate superior efficacy over human and plant exosomes without ethical concerns or regulatory hurdles.” But how do these molecules “communicate” with human cells? Dr. Ablon explains that Lactobacillus exosomes interact naturally with human cells because Lactobacillus is a bacterium commonly found in the human microbiome. “This makes its exosomes biocompatible and easily absorbed without resistance,” she adds.

Exo Booster is designed to accelerate post-procedure recovery after treatments like microneedling, chemical peels and laser resurfacing. “It enhances the skin’s natural healing process by reducing inflammation, soothing irritation and promoting faster cell regeneration,” says Vuong. “Exo Booster also improves overall texture, tone and resilience. We have seen patients show improvement in less than 30 minutes. Even we were surprised. Over time, it can boost hydration, trigger collagen production, minimize redness and optimize the results of clinical treatments, too.”

In a split-face clinical study on 30 participants, Exo Booster performed superior to human exosomes after aesthetic in-office procedures including ablative and nonablative lasers and traditional and radio-frequency microneedling. “These treatments create micro-channels in the skin, allowing deep penetration of Exo Booster’s active exosomes,” says Dr. Ablon. The serum is applied post-procedure and then patients are given the remaining solution to take home and apply twice daily for seven days post-treatment.

Other impressive results came from a clinical study on 32 participants who had a microneedling procedure. Results revealed that those who also received Exo Booster had an 86-percent reduction in the appearance of wrinkles compared to those who had microneedling alone. This group also experienced a 46-percent increase in skin resilience. Results were measured 21 days post-op. “As aesthetic treatments evolve, innovations like this highlight the importance of post-procedure care in achieving optimal outcomes and maintaining healthy, youthful skin,” adds Vuong.