7 Skin-Firming Serums to Try Right Now

SkinCeuticals A.G.E. Interrupter Ultra Serum ($185)

In their practice, Palo Alto, CA facial plastic surgeons David Lieberman, MD and Sachin Parikh, MD highlight this serum for patients noticing loss of firmness. With 30 percent Proxylane, it targets elasticity across the forehead, cheeks, jawline and neck.

BUY ON DERMSTORE - $185

BUY ON BLUE MERCURY - $185

NassifMD Hydro-Screen Hydrating Serum ($82)

Beverly Hills facial plastic surgeon Paul S. Nassif, MD originally developed this serum for his surgical patients. “I needed something that would deliver intense hydration while helping skin look smoother and more supple long term,” he says. The formula is designed for the face, neck and even hands, where sagging and crepiness often appear first.

BUY ON NASSIFMD - $82

BUY ON NORDSTROM - $82

Nakery Beauty SkinRepair Retinol Deep Wrinkle Serum ($44)

This formula blends encapsulated retinol with NAD+ complex and ceramides to firm without irritation. “Retinoids are well-known for increasing cell turnover and stimulating collagen production, which helps reduce sagging and improve skin texture,” says Pittsburgh plastic surgeon Jeffrey Antimarino, MD.

BUY NOW - $44

Beekman 1802 Milk RX Advanced Better Aging Serum ($72)

This serum uses goat milk exosomes, liquid collagen and stable vitamin C to brighten skin and reduce the look of fine lines and wrinkles. “Vitamin C not only brightens the skin but also protects collagen from free radical damage and aids in its production,” says Dr. Antimarino.

BUY ON BEEKMAN 1802 - $72

BUY ON ULTA - $72

Marini SkinSolutions NeuroSmooth ($198)

This peptide-powered serum is designed to ease micro-tension in the skin’s surface while softening the look of pores and supporting collagen and elastin. “Peptides act as cellular messengers to stimulate collagen and elastin production,” says Dr. Nassif. The formula also includes soothing and antioxidant ingredients to round out its skin-smoothing benefits.

BUY NOW - $198

Repêchage Triple Action Lift Peptide Serum ($130)

Speaking of peptides, this serum delivers four of them—Acetyl Hexapeptide-8, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7—along with nutrient-rich seaweed extracts and Mirabilis Jalapa to calm and hydrate. Together, these ingredients are formulated to help support firmer, smoother, well-hydrated skin.

BUY NOW - $130

Parëva Beauty C35.5 Firming Glow Serum ($72)

Formulated with Swiss plant stem cells and antioxidant curcumin, this serum is designed to help improve the look of firmness and brightness while supporting skin’s defenses against free-radical damage. “The key is combining peptides, retinol, antioxidants and barrier-strengthening ingredients. This synergy provides both immediate visible tightening and long-term structural support,” says Dr. Nassif.

BUY NOW - $72

BUY ON CREDO BEAUTY - $74