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Readers in Their 40s Say This Anti-Aging Serum Makes a ‘Noticeable Difference’ 

Readers in Their 40s Say This Anti-Aging Serum Makes a ‘Noticeable Difference’  featured image
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While it may seem like there’s a new “miracle” product launching daily, there’s one serum that’s long earned a devoted following by both skin experts and consumers alike. SkinMedica TNS Advanced+ Serum ($295) isn’t riding the wave of social media hype or celebrity endorsements—instead, it’s winning over users through pure results.

The secret to its success? According to recent survey data from 1,300+ NewBeauty readers,* its growth factor– and peptides–infused formula is delivering the kind of visible changes that make users do a double-take in the mirror.

The Sweet Spot

SkinMedica’s TNS Advanced+ Serum seems to particularly resonate with NewBeauty readers in their mid-40s who are seeing dramatic changes in their skin. 

“I genuinely see results when using [it] regularly and a noticeable difference when I stop using it,” shares a 46-year-old user. Another reader at the same age specifically praised the growth factors, noting “I actually see improvement with regular use.”

But it’s not reserved for those 40-plus. Even those in their 30s are jumping on board, with a 38-year-old user putting it simply: “it works.” 

The Reality Check 

Unlike some serums where results are questionable at best, users actually notice when they stop using this one. Multiple reviewers in their 40s noted seeing changes both when maintaining consistent use and when taking a break. One 46-year-old user noted she noticed results “soon after beginning my TNS regimen” and a “noticeable difference when I stopped using it.”

How it Works

The magic behind this serum lies in its innovative dual-chamber design. One chamber houses a powerful growth factor blend enriched with peptides, while the other contains a mix of botanicals, marine extracts and more peptides that work together to rejuvenate skin. Each press of the pump delivers a perfect dose of both formulas, keeping the ingredients fresh and potent until the moment they touch your skin.

So while the TNS Advanced+ Serum sits firmly in luxury skin-care territory, the high-tech science and consistent feedback about visible results prove it’s earning its keep on bathroom counters. 

skinmedica tns advanced

BUY ON AMAZON – $295

BUY ON DERMSTORE – $295

*Source: BeautyEngine Advanced Research, 2024

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