A supplement in development in Japan modestly improved the appearance of crow’s-feet in post-menopausal women, according to a study published in the journal Menopause. The researchers tested the effects of the supplement S-equol on post-menopausal women for 12 weeks. The supplement is believed to attach itself to estrogen receptors and act as estrogen. The researchers were especially interested in the estrogen’s effect on slowing the aging of skin.
The body naturally makes S-equol, and women who produce more of it are said to have fewer or less-severe menopausal symptoms. However, because estrogen has been shown to increase the risk of breast and uterine cancers, more studies are needed to determine the safety of adding an estrogen-boosting supplement. However, the researchers in said they saw no differences in the women’s breast or uterine tissue during the course of the study.
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