Platelet-Fat Combo Increases Blood Vessels, Study Finds

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Selphyl, a type of filler material made from a patient’s own blood, is getting a lot of buzz for its effectiveness, low cost and reduced risk of rejection. Now, researchers have found that Selphyl helps to increase blood vessels, which may make fat injection results last longer.

Platelet-rich fibrin matrix (PRFM), which goes by the name Selphyl or the vampire facelift, is created by drawing the patient’s blood and separating out the platelets, which are then often combined with the patient’s fat (which has been removed through liposuction). The combination is used as a filler for crow’s-feet, under-eye puffiness, cheek fullness and more.

Researchers in the study set out to determine the benefits and efficacy of fat transfer with PRFM. A 37-year-old woman had fat removed from her outer thighs and injected into her lower abdomen in two areas-one with 8 ccs of fat only and one with 8 ccs of fat plus 4 ccs Selphyl.

After eight weeks, they found viable fat in both injections sites. However, the Selphyl site showed an increase in blood vessels, which is essential for long-term fat survival.

“The result of this case study indicates that fat mixed with Selphyl may improve graft survival by increasing both neovascularization and total cell number,” the authors wrote in the study that was published in the American Journal of Cosmetic Surgery.

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