The Genetic Secrets Of Cellulite

There are numerous theories for why some women suffer with cellulite and others don't, not to mention plenty of promises about treatments. However, a new study may have finally pinpointed the most biologically fundamental reasons behind the orange-peel problem.

Led by Dr. Enzo Emanuele, researchers at Italy's University of Pavia divided 400 healthy-weight women into two groups: those with cellulite and those without. Ultimately, they found variants among two genes, ACE and H1F1A, which could imply the usefulness of certain treatments.

For example, due to the nature of the H1F1A gene, the researchers say carboxytherapy or ozone therapy may make a difference in some women's cellulite. However, it's the ACE findings that may lead to a whole new approach in the battle against lumpiness.

Those with cellulite were shown to have more ACE (angiotensin-converting enzyme) in their tissues, which could mean it's having an effect on blood flow in the affected areas. The researchers propose that a topical application of a pharmacological ACE inhibitor, such as captopril, could serve as a genetically targeted treatment for cellulite.

Although this research holds a lot of potential for future cellulite solutions, more research must be done to confirm the findings before products and procedures are introduced.

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