How Hyperpigmentation Happens

The majority of cells in the epidermis are skin cells, which create a protective layer. But about every eighth cell is a melanocyte cell, which makes melanin. Melanin is produced in the lower levels of the skin, and the pigmentation process resembles that of an assembly line.

First a trigger-the sun, inflammation, injury or hormones-sends a signal to the melanin-stimulating hormones. After this message is sent, the enzyme tyrosinase is activated. Once tyrosinase is signaled, the melanocyte cell receives a message to produce pigment. The melanocytes make melanin and package them into little bundles known as melanosomes. The cells then disperse pigment upward through the dermis, resulting in hyperpigmentation.

Because the body can't divvy up the pigment properly, it gets deposited in clumps that show up as spots and discoloration. As the skin ages, the cycle is less controlled (sun exposure and hormonal changes interrupt it), and the steady distribution of melanin becomes more diffuse. As excess melanin is produced, hyperpigmentation forms, creating deposits of color that stay indefinitely unless treated.

3 Comments
  • Richard Schulz
    Posted on

    Hi, thanks for the article, have you ever heard of {Nerium AD}, my wife has been using it for about 2 weeks now and to my surprise it seems to be really helping, the skin coloring has improved and it seems to be smoother. Thanks again

  • anonymous
    Posted on

    polka dot, have you ever been on this site before? just click on the hyperpigmentation tag at the end of the article and you'll see pages of articles about solutions and products.

  • polka dot
    Posted on

    Thank you for the information on hyperpigmentation happens, but how do you get rid of it??????

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