The majority of weight-loss drugs in America work by regulating appetite hormones or increasing metabolism so that we burn fat and calories faster. And most of those diet drugs have a hard time staying on the market or getting FDA approval in the first place. A new weight-loss drug, being developed in Texas, takes a different approach.
The new diet drug targets blood vessels of white fat tissue and obliterates fat cells with a synthetic protein. The dead cells simply get reabsorbed, the researchers at the University of Texas M.D. Anderson Cancer Center reported in the journal Science Translation Medicine.
So far they have only tried the weight-loss drug, called Adipotide, on monkeys. The obese monkeys lost 27 percent of abdominal fat and had better insulin function with no side effects, while lean monkeys stayed the same weight. However, a month after the newly svelte monkeys stopped taking Adipotide, they started plumping back up.
The next step will be on human trials. What do you think? Will science ever find a safe, effective weight-loss drug?
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